DRIVE Meeting 2027 Agenda

The Biology of DRIVE

Connecting ancestral biology, representative clinical research, patient outcomes, and practical strategies for improving DRIVE scores.
Friday, March 12th, 2027

Meeting Chair: Ruemu E. Birhiray

Time Session Title
6:30 AM - 7:00 AM Continental Breakfast
7:00 AM - 7:10 AM The Biology of DRIVE: Connecting Discovery, Representation, and Better Care
Ruemu E. Birhiray, MD

Session 1: The Ancestral Biology of Cancer

Time Event/Topic
7:10 AM - 7:25 AM Beyond the Average Patient: Ancestral Genomic Variation and Its Implications for Hematologic Cancer Care
Andrew Hantel, MD, MPH
7:25 AM - 7:40 AM The Signals of Senescence: SASP, Ancestry, and the Cancer Microenvironment
Sanket Shah, PhD
7:40 AM - 7:55 AM Duffy-Null, Different Decisions: Interpreting Blood Counts and Outcomes in Multiple Myeloma
Paul Richardson, MD
7:55 AM - 8:10 AM Ancestry at the Bedside: Connecting Breast Cancer Biology to Treatment Decisions
Bryan Schneider, MD
8:10 AM - 8:25 AM From Biological Variation to Clinical Action: Questions and Panel Discussion
8:25 AM - 8:35 AM Coffee Break

Session 2: Strategies for Improving DRIVE Scores

Time Event/Topic
8:35 AM - 8:50 AM Whose Evidence Gets Heard? Ancestry Representation in Publications and Scientific Presentations
Catherine Lai, MD, MPH
8:50 AM - 9:05 AM Artificial Intelligence at the Intersection: Using Ancestry and AI to Build More Representative Clinical Trials
Eimear Kenny, PhD²
9:05 AM - 9:20 AM Tomorrow's Investigators, Today's Opportunity: Bringing Clinical Trial Education into Medical School
Maya Birhiray
9:20 AM - 9:35 AM Raising the Score, Strengthening the Evidence: Questions and Panel Discussion
9:35 AM - 9:45 AM Coffee Break

Session 3: What Happens When DRIVE Fails

Time Event/Topic
9:45 AM - 10:00 AM When DRIVE Fails: Duty of Care, Patient Harm, and Legal Accountability
Medha Makhlouf, JD³
10:00 AM - 10:15 AM The Cost of Being Unrepresented: What Patients Lose When Evidence Leaves Them Out
Joan Reede, MD or Merlin Chowkwanyun, PhD, MPH
10:15 AM - 10:30 AM Who Delivers the Care Matters: Representation, Cultural Alignment, and Trust in the Healthcare Team
Lisa Cooper, MD, MPH¹
10:30 AM - 10:45 AM When Evidence and Care Fall Short: Questions and Panel Discussion
10:45 AM - 10:55 AM Coffee Break

¹ Suggested speaker: Lisa Cooper, MD, MPH. Alternatives: Monica Peek, MD, MPH, MSc; Yolanda R. Lawson, MD; Uché Blackstock, MD; Linda Villarosa; or Harriet A. Washington.

Session 4: Tommorow’s Steps

Time Event/Topic
10:55 AM - 11:25 AM Keynote Conversation: The Next Chapter in DRIVE — From Commitment to Measurable Change
Robert Winn, MD
11:25 AM - 11:40 AM Evidence That Serves Every Patient: A Public Policy Approach to Cancer Treatment Decisions
Speaker TBD⁴
11:40 AM - 11:55 AM Less Red Tape, More Representation: Building a Global Coalition for Better Clinical Trials
Edward S. Kim, MD, MBA
11:55 AM - 12:10 PM Setting the Standard: National Organizations, Data Reporting, and Abstract Selection
Belinda Avalos, MD
12:10 PM - 12:25 PM Opening the Trial Door: Practical Strategies to Improve Access and Population Representation
Carmen Guerra, MD, MSCE
12:25 PM - 12:40 PM Measuring What Matters: Biostatistical Advances and the Next DRIVE Calculator
Todd Burus, PhD, MAS
12:40 PM - 12:55 PM Tomorrow's Steps, Today's Commitments: Questions and Closing Panel Discussion
12:55 PM - 1:00 PM Closing Remarks
Ruemu E. Birhiray, MD
1:00 PM Luncheon

² Alternative speakers for Artificial Intelligence at the Intersection: James Zou, PhD; or Chunhua Weng, PhD. ³ Alternative speakers for When DRIVE Fails: Michelle Mello, JD, PhD; Dayna Bowen Matthew, JD, PhD; or I. Glenn Cohen, JD. ⁴ Suggested speakers for Evidence That Serves Every Patient: Renuka Iyer, MD (Chief Medical Officer, NCCN); Mark McClellan, MD, PhD; Otis Brawley, MD; or Ezekiel Emanuel, MD, PhD. Program planning notes: Carmen Guerra’s session title is proposed; no topic was supplied. Speaker alternatives and TBD assignments remain to be finalized.